Mr Obama's first stop is London where he is to attend the G20 summit hosted by British Prime Minister Gordon Brown.
The two will have breakfast talks in Downing Street on Wednesday followed by meetings with other world leaders.
Much is riding on the trip, says BBC North America editor Justin Webb, as the US is seen by other nations as the catalyst for global economic recovery.
Our correspondent added that although the US regards Gordon Brown as a key player in efforts to secure a lasting agreement at the G20, most of the focus would still be on the president's role.
Busy schedule
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| Gender | Male | |
| Age | 42 | |
| Location | UK, England: Hertfordshire, Watford | |
| 🌈 Sexuality | Straight | |
